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HK J Paediatr (New Series)
Vol 13. No. 1,
2008
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HK J Paediatr (New Series) 2008;13:46-52
Case Report
Hepatopulmonary Syndrome: An Unusual Presentation of Chronic Hypervitaminosis A
VWS Lau, DCY Lau, KF Huen Department of Paediatrics & Adolescent Medicine, Tseung Kwan O Hospital, 2 Po Ning Lane, Hang Hau, Tseung Kwan O, N.T., Hong Kong, China VWS Lau ( 劉慧思 ) MBBS, MECRCH DCY Lau ( 劉進源 ) MBBS, MRCP(UK), FHKCPaed KF Huen ( 禤桂芬 ) MBBS, FRCP(UK), FHKCPaed Correspondence to: Dr VWS Lau Received August 30, 2007
Abstract Vitamin supplementation is a frequent phenomenon in Hong Kong children for various reasons. Vitamin A is amongst the most frequently used vitamin presented in various 'fish oil' supplements, and its toxicity is being widely reported in literature. Hepatopulmonary syndrome is a triad of chronic liver disease; increased alveolar-arterial oxygen gradient; and evidence of intrapulmonary vascular dilatation (IPVD), and has been reported in a number of liver diseases but not in hypervitaminosis A before. We reported a case in which a family of three sisters suffered from hepatopulmonary syndrome as a result of hypervitaminosis A. Keyword : Hepatopulmonary syndrome; Hypervitaminosis A; Vitamin A Abstract in Chinese
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