Table of Contents

HK J Paediatr (New Series)
Vol 13. No. 1, 2008

HK J Paediatr (New Series) 2008;13:4-6

Invited Commentary

Serum Gamma Glutamyltransferase Levels in Cholestasis of Infancy
膽汁淤積嬰兒血清 γ谷氨酰基轉移酶(GGT)水平

K Tse


Abstract

Serum gamma glutamyltransferase (GGT) level in cholestasis of infancy is a complex issue. Experience and caution are required in its interpretation. The common differential lists mentioned in the literatures, including different types of Progressive Familial Intrahepatic Cholestasis and bile acid synthetic disorders, are discussed. Other causes of cholestasis of infancy with normal serum GGT, such as, Smith-Lemli-Opitz Syndrome, Arthrogryposis multiplex congenita, Renal dysfunction and Cholestasis (ARC) Syndrome are also mentioned.

對膽汁淤積嬰兒的血清γ谷氨酰基轉移酶(GGT)水平的探討是一複雜的課題,需要憑藉豐富的經驗謹慎地解釋它的概念。文獻中所提到的最常見鑒別,包括不同類型的家族進展性肝內膽汁淤積以及膽汁酸合成紊亂。同時還提到了其他引起血清 GGT 水平正常的嬰兒膽汁淤積的原因,例如:Smith-Lemli-Opitz 綜合徵、先天多發性關節攣縮、腎功能不全及膽汁淤積綜合徵( ARC)。

Keyword : Bile acid synthetic disorders; Cholestasis; Gamma glutamyltransferase; Infant; Progressive Familial Intrahepatic Cholestasis

關鍵詞:膽汁酸合成紊亂、膽汁淤積症、γ 谷氨酰基轉移酶、嬰兒、家族進展性肝內膽汁淤積

 
 

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