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HK J Paediatr (New Series)
Vol 13. No. 1,
2008
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HK J Paediatr (New Series) 2008;13:4-6
Invited Commentary
Serum Gamma Glutamyltransferase Levels in Cholestasis of Infancy
K Tse Department of Paediatrics & Adolescent Medicine, Tuen Mun Hospital, Tsing Chung Koon Road, Tuen Mun, N.T., Hong Kong, China K Tse ( 謝江 ) FRCP (Edin), FHKCPaed, FHKAM (Paed) Correspondence to: Dr K Tse Received October 13, 2007
Abstract Serum gamma glutamyltransferase (GGT) level in cholestasis of infancy is a complex issue. Experience and caution are required in its interpretation. The common differential lists mentioned in the literatures, including different types of Progressive Familial Intrahepatic Cholestasis and bile acid synthetic disorders, are discussed. Other causes of cholestasis of infancy with normal serum GGT, such as, Smith-Lemli-Opitz Syndrome, Arthrogryposis multiplex congenita, Renal dysfunction and Cholestasis (ARC) Syndrome are also mentioned. Keyword : Bile acid synthetic disorders; Cholestasis; Gamma glutamyltransferase; Infant; Progressive Familial Intrahepatic Cholestasis
Abstract in Chinese
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