Table of Contents

HK J Paediatr (New Series)
Vol 3. No. 1, 1998

HK J Paediatr (New Series) 1998;3:68-70

Case Report

Treating Factor VII Deficiency: Fresh Frozen Plasma or Factor VII Concentrate?

ACW Lee, KW Wong, SC Szeto, KS Tong, KT So


Abstract

A 3-year-old Chinese boy with congenital factor VII deficiency presented with recurrent gastrointestinal bleeding, epistaxis, hemarthrosis and soft tissue bleeding. The hemorrhagic symptoms were ameliorated with infusions of fresh frozen plasma, but it was complicated by hyperalbuminemia, hypergammaglobulinemia and hypertension. When the treatment was switched to plasma-derived factor VII concentrate, hemostatic control improved with resolution of the complications, Although factor VII concentrate is expensive, it may be the preferred treatment in the patient with severe factor VII deficiency in terms of clinical efficacy and cost effectiveness.

Keyword : Child; Factor VII concentrate; Factor VII deficiency; Treatment


Abstract in Chinese

 
 

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