SM Md Ali, Z Mat Saad, NZ Mohamad Yusof, MF Mustafa

Abstract

The study investigates factors influencing parental decision-making in paediatric clinical trials through in-depth interviews with parents at two hospitals in Northern Malaysia. Key findings reveal that parents' previous experiences with clinical care significantly impact their willingness to participate, with trust in healthcare providers and effective communication being essential. Parents are more inclined to enroll when they perceive their child's condition as serious and believe the trial offers better treatment options. Economic considerations also play a crucial role, as many parents are drawn to the cost-effective care provided during trials, alleviating financial burdens. The study emphasizes the importance of enhancing communication skills among healthcare professionals and building trust to increase parental participation in clinical research. Ultimately, a collaborative approach between healthcare providers and families is crucial to strengthen paediatric clinical trials, ensuring children benefit from advancements in medical treatments and receive safe, effective care tailored to their needs.