MJ Yang, ZC Zheng, XO Shan, J Lin

Abstract

Rapid-onset obesity with hypoventilation, hypothalamic dysfunction, and autonomic dysregulation (ROHHAD) syndrome is a rare, but life-threatening disease. The value of monitoring D-dimer levels in ROHHAD syndrome cases remains to be determined. Here, we present a 9-year-old boy with ROHHAD syndrome who had a high level of D-dimer before surgery for an adrenal tumour but fell to normal following surgical excision. ROHHAD syndrome patients may be at risk of thrombosis. Changes in D-dimer level may be used as a marker to help predict the development of neural crest tumour in ROHHAD syndrome patients.