Table of Contents

HK J Paediatr (New Series)
Vol 16. No. 4, 2011

HK J Paediatr (New Series) 2011;16;278-284

Case Report

Parainfluenza Infection Associated Acute Necrotising Encephalopathy: Survival Despite Initial Fulminant Neurological Presentation

STH Fung, KCH Lau, SWW Cherk, EYL Kan


We report a 19-month-old toddler who developed and survived an episode of acute necrotising encephalopathy, as suggested by typical rapidly deteriorating consciousness and seizures (status epilepticus) associated with parainfluenza infection and typical MRI brain features of multiple symmetrical involvement of bilateral thalami, brainstem and periventricular white matter. Despite the initial fulminant course, the child survived with moderate residual neurological deficits. We hope to raise the awareness of this rare presentation of parainfluenza infections and the importance of early aggressive treatment that may substantially improve the previous notoriously high mortality rate or poor neurological outcome.

Keyword : Acute necrotising encephalopathy; Child; Influenza infection; Parainfluenza infection

Abstract in Chinese


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