KL Kwong, H Hui, CM Hui, TL Que

Abstract

We report a 5-year old boy with influenza A-associated acute necrotising encephalopathy. This is the first reported case in Hong Kong. The diagnosis was based on clinical features, neuroimaging findings and isolation of influenza A virus from nasopharyngeal aspirate. The disease is characterised by fever, seizure, rapid deterioration in consciousness and radiologic involvement of bilateral thalami and cerebellum. Paediatricians taking care of children should be aware of this exceedingly rare but emerging presentation of influenza infections.

我們報導一例 5 歲男孩，患甲型流行性感冒合併急性壞死性腦病。這是香港關於這方面的首例報導。診斷依據為：臨床表現、神經影像表現和鼻咽分泌物中分離出甲型流感病毒。其中具有特徵意義的為發熱、抽搐、神志急劇轉壞和影像學上顯示雙側丘腦和小腦受累。兒科醫生在診療上必須特別注意流行性感冒在這方面的罕見而緊急的表現。