Table of Contents

HK J Paediatr (New Series)
Vol 11. No. 3, 2006

HK J Paediatr (New Series) 2006;11:246-254

Other Articles

Probiotics Provoked D-lactic Acidosis in Short Bowel Syndrome: Case Report and Literature Review

WH Ku, DCY Lau, KF Huen


D-lactic acidosis is a rare complication of short bowel syndrome. Clinically there are episodes of encephalopathy and metabolic acidosis with an increased anion gap. Formation of D-lactic acid by the abnormal gut flora, together with its impaired metabolism results in its accumulation and subsequent effect on the central nervous system. In this article we reported a boy with short bowel syndrome and D-lactic acidosis provoked by ingestion of probiotics. The probiotics are in the form of capsules and probiotic-containing formula. We had also reviewed the paediatric cases of D-lactic acidosis and discussed its biochemistry, pathogenesis, clinical features, diagnosis and treatment. With more understanding of its mechanism, we stated that D-lactic acidosis can be treated as well as provoked by probiotics.

Keyword : D-lactic acidosis; Paediatric; Probiotics; Short bowel syndrome

Abstract in Chinese


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